🧠 Pituitary & Growth Hormone Disorders: Key Medicines in India
🔹 Introduction
Pituitary gland ko “master gland” kaha jata hai kyunki ye multiple hormones control karti hai — jaise growth hormone, prolactin, ACTH, TSH, LH, FSH. Agar pituitary dysfunction hota hai, to patients mein growth disorders, acromegaly, infertility aur prolactinomas jaisi conditions develop ho sakti hain.
In disorders ke management ke liye doctors specific hormone replacements ya hormone-blocking drugs prescribe karte hain.
🔹 1. Recombinant Growth Hormone (GH)
- Drug: Somatropin
- Brands: Humatrope, Genotropin
- Use:
- GH deficiency in children (short stature, delayed growth)
- Adult GH deficiency
- Notes: Expensive therapy; dose adjust hoti hai age & weight ke hisaab se
🔹 2. Somatostatin Analogues
- Drug: Octreotide
- Brand: Sandostatin
- Use:
- Acromegaly (excess GH production)
- Certain pituitary & neuroendocrine tumors
- Notes: Injection form; long-acting depot formulations bhi available hain
🔹 3. Dopamine Agonists (for Prolactinoma)
- Drugs & Brands:
- Cabergoline → Dostinex
- Bromocriptine → Parlodel
- Use:
- Prolactinomas (reduce prolactin levels, shrink tumor)
- Infertility related to high prolactin
- Notes: Usually well-tolerated, oral tablets
📝 Conclusion
Pituitary disorders ka management highly specialized hota hai:
- GH deficiency → Somatropin (GH therapy)
- Excess GH (Acromegaly) → Octreotide
- Prolactinoma → Cabergoline, Bromocriptine
Har patient ke liye therapy individualized hoti hai, isliye regular hormone monitoring aur endocrinologist supervision bahut zaruri hai.
⚠️ Disclaimer
This article is for educational purposes only. It is not a substitute for medical advice. Always consult an endocrinologist before starting or changing any pituitary disorder treatment.