⚕️ Pancreatic Disorders: Key Medicines & Brands in India
🔹 Introduction
Pancreas do main functions perform karta hai:
- Exocrine function → Digestive enzymes production
- Endocrine function → Hormone secretion (insulin, glucagon)
Pancreatic disorders jaise:
- Chronic pancreatitis
- Pancreatic enzyme deficiency (post-surgery, cystic fibrosis)
- Pancreatic fistula or secretory diarrhea
- Neuroendocrine tumors
Inka management enzyme replacement & symptom control par based hota hai.
🔹 1. Pancreatic Enzyme Supplements
✦ Pancrelipase
- Brand: Creon, Pancreatin
- Use:
- Chronic pancreatitis
- Exocrine pancreatic insufficiency (post-pancreatic surgery, cystic fibrosis)
- Note: Capsules contain lipase, amylase & protease; taken with meals to aid digestion
✦ Other Enzyme Preparations
- Brands: Panzytrat, Pancrex
- Use: Same as above
- Note: Dose titrated based on fat content of meals and patient response
🔹 2. Somatostatin Analogues
✦ Octreotide
- Brand: Sandostatin
- Use:
- Neuroendocrine tumors
- Pancreatic fistula
- Secretory diarrhea due to VIPoma or other tumors
- Note: Reduces hormone secretion & GI fluid loss; available in short-acting & long-acting depot injections
🔹 3. Supportive Therapy
- Nutritional support → High-calorie diet, fat-soluble vitamins (A, D, E, K) supplementation
- Pain management → Analgesics (avoid chronic opioids if possible)
- Monitoring → Regular assessment of enzyme efficacy & nutritional status
📝 Conclusion
Pancreatic disorders ka management largely symptomatic & replacement therapy par depend karta hai:
- Pancreatic enzymes (Creon, Pancrelipase) → Aid digestion in exocrine insufficiency
- Octreotide (Sandostatin) → Control hormone secretion & secretory diarrhea in pancreatic tumors
- Supportive care aur nutrition monitoring equally important
⚠️ Disclaimer
This article is for educational purposes only. It is not a substitute for professional medical advice. Always consult a gastroenterologist or endocrinologist before starting pancreatic enzyme therapy or octreotide.