🦴 Osteoporosis and Calcium Metabolism: Key Medicines in India
Osteoporosis and Calcium Metabolism:
🔹 Introduction
Osteoporosis ek chronic bone disease hai jisme bones weak aur fragile ho jaati hain, fracture risk badh jata hai. India mein, yeh problem zyada tar post-menopausal women aur elderly patients mein dekhi jaati hai.
Bone health maintain karne ke liye doctors prescribe karte hain calcium supplements, vitamin D aur specific osteoporosis medicines.
🔹 1. Calcium Supplements
- Examples / Brands:
- Calcium Carbonate → Calcium Sandoz
- Calcium Citrate → Caltrate
- Use: Bone strength maintain karna, deficiency cover karna
- Note: Best absorbed with vitamin D
🔹 2. Vitamin D
- Drug: Cholecalciferol (Vitamin D3)
- Brands: Calcirol, Vitamin D3 sachets/tablets
- Use: Calcium absorption improve karta hai, deficiency correct karta hai
- Note: Commonly prescribed as weekly sachets in India
🔹 3. Bisphosphonates
- Examples / Brands:
- Alendronate → Alendron, Fosamax
- Risedronate → Actonel
- Mechanism: Bone resorption (breakdown) slow karte hain → fracture risk reduce
- Use: First-line therapy in postmenopausal osteoporosis
- Note: Empty stomach lena hota hai; patient ko 30 mins tak upright rehna padta hai (esophageal irritation avoid karne ke liye)
🔹 4. Denosumab (RANKL Inhibitor)
- Brand: Prolia
- Mechanism: Monoclonal antibody → osteoclast activity block karta hai → bone loss prevent
- Use: Severe osteoporosis, high fracture risk
- Note: Injection form, 6 monthly dosing
📝 Conclusion
Osteoporosis treatment mein calcium + vitamin D foundation therapy hai, jabki bisphosphonates aur denosumab advanced cases ke liye use hote hain.
Doctor har patient ke age, fracture risk aur medical condition ke hisaab se therapy choose karte hain.
⚠️ Disclaimer – MR ki Baat
This article is for educational purposes only. It is not a substitute for medical advice. Please consult your doctor or endocrinologist for proper diagnosis and treatment of osteoporosis.