Liver Disorders

⚕️ Liver Disorders: Key Medicines & Brands in India

🔹 Introduction

Liver ek vital organ hai jo digestion, detoxification aur metabolism mein central role play karta hai. Liver disorders jaise:

  • Gallstones / Cholestasis
  • Fatty Liver Disease
  • Cirrhosis / Hepatic Encephalopathy
  • Viral Hepatitis (B & C)
  • Alcoholic Liver Disease

kaafi common hain. Inka treatment disease ke cause aur severity par depend karta hai. Yahaan hum commonly used liver-specific molecules aur unke brand names dekhte hain.

🔹 1. Bile Acid Therapy

✦ Ursodeoxycholic Acid (UDCA)

  • Brands: Ursofalk, Ursocol, Udiliv
  • Use:
    • Gallstones dissolution (non-surgical cases)
    • Primary biliary cholangitis, cholestatic liver diseases
  • Note: Improves bile flow and protects liver cells

🔹 2. Hepatoprotective Agents

✦ Silymarin

  • Brand: Silybon
  • Use: Supportive treatment in liver injury (alcoholic liver disease, drug-induced hepatitis)
  • Note: Herbal flavonoid extract from milk thistle, antioxidant properties

✦ L-Ornithine L-Aspartate (LOLA)

  • Brand: Hepamerz
  • Use: Reduces ammonia levels in hepatic encephalopathy
  • Note: Helps improve mental status in cirrhosis patients

🔹 3. Antivirals for Hepatitis B

✦ Tenofovir

  • Brands: Viread, Tenvir
  • Use: Chronic Hepatitis B infection
  • Note: Potent, first-line therapy; long-term use required

✦ Entecavir

  • Brands: Baraclude, Entavir
  • Use: Hepatitis B, effective in resistant cases
  • Note: High barrier to resistance

🔹 4. Antivirals for Hepatitis C

✦ Sofosbuvir + Velpatasvir

  • Brand: Velpanat
  • Use: Chronic Hepatitis C infection (all genotypes)
  • Note: Oral combination, high cure rates (>95%)

✦ Ledipasvir + Sofosbuvir

  • Brand: Harvoni
  • Use: Alternative oral combination for Hepatitis C
  • Note: Short duration (12 weeks) therapy in most cases

🔹 5. Other Supportive Therapies

  • Vitamin E: Non-alcoholic fatty liver disease (NAFLD)
  • Zinc & Nutritional support: For cirrhosis patients
  • Lactulose: Sometimes used in hepatic encephalopathy (along with LOLA)

📝 Conclusion

Liver disorders ka management multifactorial hai:

  • UDCA → for gallstones & cholestasis
  • Silymarin, LOLA → hepatoprotective & supportive
  • Antivirals (Tenofovir, Entecavir, Sofosbuvir combos) → for viral hepatitis
  • Lifestyle modification (alcohol abstinence, diet control, weight management) is equally important.

⚠️ Disclaimer

This content is for educational purposes only. It is not a substitute for medical advice. Always consult a hepatologist or gastroenterologist before starting liver disease treatment.

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